Buflomedil Hydrochloride (brand name Loftyl) is a vasoactive medication used to treat claudication and peripheral artery disease symptoms. Buflomedil Hydrochloride has been used to treat disorders of the leg arteries and has shown some promise in the treatment of persons who have had a stroke. The most frequent type of stroke is caused by a blockage or constriction of a cerebral artery (i.e. ischaemic stroke). Buflomedil Hydrochloride is a medication that helps widen blood arteries in the brain, which may help people who have had an ischemic stroke. In practical practice, however, it has not been licensed to treat stroke. Because of concerns of severe neurological and cardiac toxicity, this medicine has been taken off the market in the European Union. The European Medicines Agency (EMA) recommended that clinicians avoid using buflomedil and investigate alternate treatment alternatives in a news release dated November 17, 2011. All member states were urged by the European Commission to revoke marketing authorization. The FDA has received reports of a variety of side effects. The Food and Drug Administration (FDA) has not yet approved it for use in the United States. Tablet is a brand name that is currently accessible.

Buflomedil hydrochloride is a vasoactive medication that has a number of different effects. It's a mild calcium channel blocker and an alpha-adrenoceptor antagonist. Platelet aggregation is inhibited, and erythrocyte deformability is improved. Its method of action in peripheral vascular disease, on the other hand, remains unknown.

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