Generics 1

Originals

Biosimilars

Medical devices

Nutraceuticals

Filters

Diphenhydramine hydrochloride manufacturers

1 products found

Filters

Filters

Filters , active

Country of origin : Ukraine

Clear all

1 products found

diphenhydramine hydrochloride

Tablets 50 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Ukraine
GMP approvals
Ukraine
Manufacturer #21582

Manufacturer usually replies in nan days

Want to see all 1 products?

Subscribe today to benefit from:

  • Streamlined product sourcing - the leading CTD dossiers database focused on finished dosage formulations

  • Direct negotiations - connect and negotiate directly with manufacturers without any brokerage fee

  • Increased profitability - secure the best commercial terms for your business by comparing offers from several manufacturers

Request Subscription

Diphenhydramine Hydrochloride

Diphenhydramine Hydrochloride as the name suggests is the hydrochloride salt form of diphenhydramine. It is a first-generation histamine antagonist and an ethanolamine with anti- allergic activity. Diphenhydramine Hydrochloride relieves symptoms of red, irritated, itchy, watery eyes, sneezing, runny nose caused by hay fever, allergies, or the common cold and cough caused by airway irritation. It has antiemetic, antitussive, hypnotic, and antiparkinson properties. When used to cure allergies, its receptors exist both peripherally and in the CNS and can sedate as an antagonist of histamine H1 receptors in the CNS. Due to its sedative effect, it is not the first choice of medicine for curing allergies. However, it has been used in many non-prescription OTC sleep medicines and cough-and-cold medications sold for nighttime use. Diphenhydramine Hydrochloride is sold under the brand names like Allerdryl, Benadryl, Benhydramin and Benylin to name a few. George Rieveschl, a former professor at the University of Cincinnati discovered it in 1943. It has the distinction of being the first prescription antihistamine approved by the U.S. FDA In 1946. Further research in the 1960s revealed that its effective in inhibiting the reuptake of neurotransmitter serotonin.

Dosage and administration

Diphenhydramine Hydrochloride is sold as tablets and capsules. The recommended dose for adults and children older than 12 years is 25 mg to 50 mg or 1 to 2 capsules. The pediatric dose for children aged 6 to 12 years, is 12.5 mg. and parents should consult for dose in kids younger than 6 years.

The cost of Diphenhydramine Hydrochloride

In the USA, the consumers pay an average retail price of $5 for a generic 30 capsules of 25mg. However, this medicine is significantly cheaper in the developing world. In India, for 20 capsules, the consumers pay an average retail price of USD0.40 or 40 cents.

How does Diphenhydramine Hydrochloride Work?

Diphenhydramine hydrochloride competitively blocks H1receptors. This results in the prevention of histamine actions on bronchial smooth muscle, capillaries, and gastrointestinal smooth muscle. This achieves the desired reduction in histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms. Diphenhydramine hydrochloride has antitussive, hypnotic, antiemetic, and antiparkinson actions. In its actions in curing allergies, its receptors exist both peripherally and in the CNS and can sedate as an antagonist of histamine H1 receptors in the CNS. Due to its sedative effect, it is not the first choice of medicine for curing allergies.

Finding Dioctahedral smectite Manufacturers and Suppliers:

The process of finding trusted Dioctahedral smectite manufacturers and Dioctahedral smectite suppliers can be made quicker and more accessible by using Pipelinepharma's an online platform, a B2B marketplace that lets you finalize the deals of pharmaceutical products in a matter of a few clicks. Also, it is an easy to use an online platform to grow your business opportunities. The robust search engine makes it convenient to search for manufacturers and suppliers of Dioctahedral smectite. The search can be further refined with industry-specific filters such as dossier type, country of origin, GMP approvals, and search criteria for Wholesaler, etc. helping to get in contact with the preferred manufacturer and supplier readily.