A GLP-1 agonist called dulaglutide is used to treat type 2 diabetes mellitus. In addition to diet and exercise, dulaglutide, sold by Eli Lilly under the brand name Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 receptor agonist that was created utilising recombinant DNA technology. In February 2020, the FDA approved the use of dulaglutide in patients with T2DM and multiple cardiovascular risk factors in order to prevent cardiovascular events. It had previously been approved by the FDA in 2014. It is the first T2DM medication licenced to lower the risk of significant adverse cardiovascular events in people receiving primary and secondary prevention. For glycemic control in individuals with type 2 diabetes mellitus, dulaglutide is used as an adjuvant therapy to diet and exercise. It is also suggested for use in adults with type 2 diabetes mellitus who have cardiovascular disease or numerous cardiovascular risk factors to lower the risk of serious adverse cardiovascular events. In people with type 2 diabetes mellitus, dulaglutide lowers blood glucose levels while fasting and after meals by antagonising the GLP-1 receptor. This medication essentially mimics the effects of human glucagon-like peptide-1, which ordinarily activates the GLP-1 receptor.

Dulaglutide stimulates the pancreatic beta cells' GLP-1 receptor, raising intracellular cyclic AMP levels. This causes beta cells to release insulin, which lowers blood glucose levels. Dulaglutide also slows stomach emptying and reduces glucagon secretion. Following subcutaneous injection, dulaglutide is gradually absorbed. Cmax occurred 24 to 48 hours after dose in a physiological study involving 20 healthy adults. Following intramuscular injection of single dosages of 0.75 mg and 1.5 mg, the average absolute absorption of dulaglutide was 65% and 47%, respectively. In a pharmacokinetic investigation, the sample proportion of dulaglutide was 3.09 L, while the apparent median value peripheral volume of distribution was around 6 L. It is assumed that dulaglutide will break down into its individual amino acids by common protein catabolism processes. There isn't much information in the literature about dulaglutide's protein binding.

It cost around $75 for the supply of 1.5 mg. Retail prices for the drug vary depending on Dulaglutide manufacturer and supplier pricing, specific formulation and on whether it is a generic or trade name variant of the drug. Also the costs of Dulaglutide vary depending on manufacturer and supplier pricing, whether it is a generic or trade name formulation, concentration of the active ingredient in the formulation. Dulaglutide is available for sale from various Dulaglutide vendors at multiple costs. Dulaglutide suppliers, on the whole, are in favor of patient aid initiatives.

PipelinePharma is the most reliable source for this medication. Finding an honest partner in our business is one of the significant challenges. To overcome this challenge and make one's life easier when looking for a direct manufacturer and supplier of Dulaglutide, one can go to the Pipelinepharma website, which assists buyers in locating dependable manufacturers and suppliers of Dulaglutide. Buyers are advised that online sellers may attempt to market fraudulent versions of the generic drug, whereas Pipeline Pharma, through its pre-auditing and quality control procedures ensures that only verified Dulaglutide manufacturers and wholesalers enter our online marketplace, offering you a risk-free B2B pharmaceutical sales platform.

Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Dulaglutide offerings can be narrowed down with filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for this substance manufacturer and Dulaglutide suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Dulaglutide. Also, each manufacturer or supplier product description contains essential information about this substance, including clinical data, stability zones, and countries in which Dulaglutide is already registered. Manufacturers also have special delivery terms.

Suppose you are a pharmaceutical licensing company or a distributor. In that case, you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the Dulaglutide suppliers. This way, the marketplace allows you as a distributor to skip the process of making a list of product manufacturers every time you are looking for in-licensing or distribution deals.

To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Dulaglutide manufacturers for the quality of the pharmaceutical products' dossiers and protect against the risk of possible malpractices.