Gemfibrozil

Gemfibrozil is used to treat abnormal blood lipid levels but less preferred than statins. Gemfibrozil is used with a proper diet to help lower triglycerides, bad cholesterol, and raise "good" cholesterol. It is a fibrate that decreases the amount of fat produced by the liver. There is a decrease in the risk of pancreatitis by lowering triglycerides. However, it may not lower the risk of a heart attack or stroke. Gemfibrozil is sold under the brand name Lopid among others. Parke Davis & Co filed for the first patent in 1968 and came into medical use in 1982. It was a result of search of compounds that lower plasma lipid levels in humans and animals. After the expiry of the initial patent, It is now available as a generic medication. In the USA, it was among the top 140 medicines, with more than four million prescriptions.

Drug forms and strengths

Gemfibrozil is sold as an oral tablet of 600 mg. the usual adult dose recommended for high cholesterol in adults aged 18–64 years is 600 mg, taken twice per day. Those 65 years and older are not advised to take this medicine if there have been kidney issues.

The price of Gemfibrozil

In the USA, it is available as a generic drug. The consumers have to pay an average cost of USD41 for 60 Tablets of 600mg. However, this medicine is more expensive in India, where a supply of 60 tablets of 600mg, would cost USD 217.

How does Gemfibrozil work?

Gemfibrozil is called Fibric acid derivatives. Its actions change the amount of cholesterol and other fats (lipids). Its actions break down fats in the blood and decrease the amount of fact produced by the liver. This helps in decreasing triglyceride levels and increasing HDL cholesterol levels.

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