Levothyroxine Manufacturers

What is Levothyroxine?

Levothyroxine is the synthetic form of the thyroid hormone thyroxine (T4), which is used to treat hypothyroidism - a condition in which the thyroid gland doesn't produce enough hormones. Levothyroxine is typically used to replace the missing thyroid hormone, which helps to regulate the body's metabolism and maintain normal growth and development. The medicine is also used to treat or prevent goiter (an enlarged thyroid gland) and to manage certain types of thyroid cancer.

Levothyroxine Sodium is the sodium salt form of Levothyroxine, which is more stable and better absorbed in the digestive system than the pure form of the hormone. Levothyroxine Sodium is the most commonly prescribed form of Levothyroxine, as it is more effective and has a longer shelf life than the pure form.

Levothyroxine was first synthesized and developed by the Belgian chemist Charles Robert Harington in 1927. However, the first company to market Levothyroxine as a treatment for hypothyroidism was Merck, which began selling the drug under the brand name Synthroid in the 1950s. Synthroid is still one of the most widely used brand-name formulations of Levothyroxine and is available in several different strengths.

Levothyroxine is available as a generic drug. It is usually taken once a day on an empty stomach, typically in the morning, with water.

Levothyroxine forms and dosage

Levothyroxine is available in several different forms, including:

• Tablet: Levothyroxine is available in tablet form and comes in several different strengths: 25 mcg, 50 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137 mcg, 150 mcg, 175 mcg, 200 mcg and 300 mcg.
• Capsule: Levothyroxine is also available in capsule form and is available in strengths of 30 mcg, 60 mcg, 90 mcg, and 120 mcg.
• Liquid: Levothyroxine is available in liquid form for patients who have difficulty swallowing tablets or capsules.

The recommended dose of Levothyroxine varies depending on the individual's age, weight, cause of hypothyroidism, and other medical conditions. It is important to follow the doctor's instructions and monitor thyroid hormone levels regularly to ensure you receive the correct dose.

Levothyroxine patent information

The original patent for Levothyroxine, under the brand name Synthroid, was first approved by the U.S. Food and Drug Administration (FDA) in the mid-1980s. The patent for Synthroid expired in the early 2000s, which allowed for the production and sale of generic versions of Levothyroxine.

After the patent expired, several companies began producing and selling generic versions of Levothyroxine, increasing availability and lowering patient costs. Today, Levothyroxine is available in brand-name and generic forms and is widely used to treat hypothyroidism.

Levothyroxine is listed on the World Health Organization's (WHO) List of Essential Medicines as the most effective and safe medicine needed in a health system. This highlights its importance and widespread use worldwide. It is also available in generic form and under various brand names in different countries, making it accessible to patients worldwide.

Levothyroxine manufacturers and suppliers

Levothyroxine is available as a generic drug. It is manufactured by several pharmaceutical companies. Some of the most well-known manufacturers of Levothyroxine include:

• Teva Pharmaceuticals
• Mylan
• Sandoz
• Watson Pharmaceuticals (Actavis)
• Lannett
• West-Ward Pharmaceuticals
• Lupin Pharmaceuticals

Levothyroxine is also available under various brand names, including Synthroid, Levoxyl, and Unithroid. In some countries, Levothyroxine may also be available as a brand-name product manufactured by a local pharmaceutical company.

Several pharmaceutical companies in Europe manufacture Levothyroxine. Some of the major manufacturers of Levothyroxine in Europe include Pfizer, Merck (MSD), Sanofi, GlaxoSmithKline (GSK), Roche, Teva Pharmaceuticals, Mylan, and Sandoz.

These companies manufacture Levothyroxine in several strengths and forms, including tablets, capsules, and liquids, and sell the drug under various brand names. In some countries, Levothyroxine may also be available as a generic drug manufactured by local pharmaceutical companies.

The wholesale price of Levothyroxine

The wholesale price of Levothyroxine can vary depending on various factors, such as the manufacturer, the strength, the dose, and the form of the drug (tablet, capsule, or liquid).

In 2021 the average wholesale price (AWP) of Levothyroxine was approximately $10 for a bottle of 100 tablets of 50 mcg strength and $35 for a bottle of 100 tablets of 100 mcg strength. However, these prices can vary widely based on a number of factors, and it is best to check with a local pharmacy or wholesaler for the most up-to-date pricing information.

Sourcing Levothyroxine in the pharma marketplace

Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing buyers with an intuitive interface that is easy to engage with. The selection of Levothyroxine options can be narrowed down with filters and easily evaluated against one another according to drug prices and commercial terms.

The advanced filters help you search for available Levothyroxine manufacturers by product ATC class, form, dossier type and readiness, country of origin, GMP approvals and more.

Also, each product card contains essential information about this substance, including clinical data, CPP, stability zones, shelf life, packs, batch sizes, MOQ, available deal types, countries where Levothyroxine is already registered or where the specific manufacturer cannot supply the product.

All this information is available to Pipelinepharma registered users and can be seen by logging into the platform free of charge.

Establishing commercial ties

If you are a pharmaceutical licensing company or a distributor, you can connect and deal with pharmaceutical manufacturers by completing the free registration and making inquiries for selected products on the Pipelinepharma marketplace. It enables you to get medicine at a reasonable price and achieve the best cost-benefit ratio for your company by avoiding the lengthy process of searching, negotiating and ordering products.

Once you have made a deal, you can expect a long-term business relationship with the Levothyroxine suppliers. The marketplace allows you, as a buyer, to include more products in the selection process each time you seek licensing or distribution deals.

Quality assurance

To comply with quality standards, including Good Manufacturing Practice (GMP) approvals held by the manufacturer of a specific medicine, we always carefully screen manufacturing companies before adding them to the platform. It allows us to ensure the quality of the Levothyroxine manufacturers' dossiers and to protect buyers from the risk of dealing with an unreliable business partner.