Megestrol Acetate Manufacturers

Megestrol Acetate belongs to a class of drugs called Antineoplastics, Hormones; Progestins; Appetite Stimulants. Megestrol acetate is used for the treatment of breast, and endometrial cancers. This drug is used as a supportive medication to treat severe loss of appetite (anorexia), and muscle wasting (cachexia) along with significant weight loss (> 10% of baseline body weight) associated with cancer and/or AIDS. Initially developed as a contraceptive, it was first evaluated in breast cancer treatment. Megestrol acetate is a synthetic progestin that exerts and effects through the various mechanisms. Weight gain tends to be associated with increase in body fat rather than muscle as a part of nutritional value. They also affect rapidly dividing normal cells, therefore are likely to suppress the bone marrow, suppress growth, impair healing, cause sterility and cause hair loss. Megestrol Acetate is marketed by Brand Name as MEGAHENZ and MEGACE ES. Megestrol comes as a tablet, an oral suspension (liquid), and a concentrated oral suspension (Megace ES) to take by mouth. Shake the liquid well before each use to mix the medication evenly. Shake the liquid well before each use to mix the medication evenly. The tablets and suspension are usually taken several times a day. The concentrated suspension is usually taken once in a day. The concentrated suspension is used in different dosages than the regular suspension. Take megestrol acetate exactly as directed by the prescription. The dosage amount of prescription of megestrol that a patient will take depends on many factors, including patients/consumers height and weight, general health or other health problems, and the type of cancer or condition that consumer possesses accordingly Physicians prescribes the dosage. Megestrol Acetate oral suspension should be stored in well-closed containers at a temperature of 15° C to 25° C (59° F to 77° F)

Wholesale Price of Megestrol Acetate

The cost for megestrol acetate oral suspension (40 mg/mL) is around $ 35.26 for a supply of 200 milliliters and the per-unit cost is available at a cost of $ 0.18 The cost for megestrol acetate oral suspension (40 mg/mL) is around $ 61.02 for a supply of 400 milliliters and the per-unit cost is available for as low as $ 0.15

Megestrol Acetate - Mechanism of action

The mechanism of megestrol acetate is explained by the production of different effects in anorexia and cachexia which is an unknown subject at the present time, but its progestin antitumour activity may involve suppression of luteinizing hormone by inhibiting the pituitary function. It is also being suggested that the megestrol's weight gain effect is related to its appetite-stimulant or metabolic effects rather than the glucocorticoid-like effects or the production of edema. Megestrol metabolites which were identified in urine constituted 5% to 8% of the dose administered in a day. It has also been suggested that megestrol may alter metabolic pathways which interfere with the production or action of mediators such as cachectin, a hormone that inhibits adipocyte lipogenic enzymes. Absorption is variable, but well absorbed orally.

Finding Megestrol Acetate Manufacturers and Suppliers

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