Mesalazine is sold under the brand names Asacol, Coltab, and Colzine and is classified as Aminosalicylates. It is used in the treatment of Ulcerative colitis, Crohn’s disease, and inflammatory bowel disease. It is available in the form of tablets, granules, rectal foam, suppositories, and enemas. It can be administered through the oral and rectal route of drug administration. It is either taken once a day in the form of tablets or granules or may be taken 2 to 3 times a day in smaller doses. It has common drug interactions with Acarbose, Acetazolamide, Acetaminophen, and Aceclofenac. Side effects associated with this pharmaceutical medicine include indigestion, stomach pain, diarrhea, high temperature, bruising, and signs of liver problems. This pharmaceutical medicine is contraindicated in conditions such as liver problems, decreased kidney function, interstitial nephritis, and change in glomerulonephritis. It is mostly excreted in urine by kidneys. It is categorized in pregnancy category C drugs. It is secreted in human milk but experts consider it safe when used during breastfeeding. It was approved by the FDA on January 16, 2007, under the brand name Lialda, manufactured by Shire development Inc.

It works by acting locally on colonic mucosa and reduces inflammation by various anti-inflammatory processes.

30 tablets of Mesalazine oral delayed-release tablets 1.2g costs around 131 dollars. Prices may differ among different dealers.

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