Nivolumab Manufacturers

Nivolumab is a medication used in the treatment of cancer to help reactivate the immune system. It is marketed as Opdivo and is a type of immunotherapy used for a number of cancers, including Hodgkin lymphoma, colon cancer, head and neck cancer, melanoma, lung cancer, and liver cancer. For some people, giving the immune system a boost in this way may help reduce the risk of cancer coming back. Nivolumab manufacturers produce the drug to be slowly injected into a vein. The intravenous infusion is given once every two weeks or every four weeks and takes about 30 minutes to one hour to administer depending on the cancer type. A plastic tube conveys the drug into the body. As everybody is different, it is important to note that the medication may cause various side effects with varying severity. Among them are nausea, diarrhea, fatigue, decreased appetite, skin rash, and joint ache. Most side effects are short-lived. Such is the importance of the supply and manufacture of nivolumab that it is on the World Health Organisation's List of Essential Medicines.

How Does Nivolumab Work?

Nivolumab is manufactured to work by blocking a protein that stops the immune system from functioning correctly. In the body, T cells (types of lymphocytes) kill cancer cells. However, the cancerous cells can evolve PD-L1 proteins to protect themselves. Nivolumab blocks these proteins. This essential immunotherapy medication was invented by a team of scientists headed by Dr. Changyu at Medarex, which was an American biopharmaceutical company based in Princeton, New Jersey. The next important step in the history of nivolumab manufacture was in 2012 with the publication of promising clinical trial results. Then in 2014, it was given the FDA (Food and Drug Administration) approval for the treatment of melanoma. Nivolumab manufacture started when it was brought to market by Bristol-Myers Squibb, which had acquired Medarex in 2009.

The Wholesale Cost of Nivolumab

Buyers wanting to know the wholesale price for an order of nivolumab can search online and find manufacturers and suppliers offering an array of different prices. In the United States, in 2019, one month's supply of nivolumab costs around US$13,556. A similar amount in the UK the previous year cost the National Health Service £5.266.

Looking for Nivolumab Manufacturers and Nivolumab Suppliers?

Buyers looking for supplies from nivolumab manufacturers and suppliers can quickly source them using Pipelinepharama's global online marketplace. Through our strict vetting and quality control procedures, you will only find verified companies.