Pantoprazole Sodium Manufacturers

Pantoprazole Sodium belongs to a class of drugs known as proton pump inhibitors (PPIs). Pantoprazole sodium is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD). This drug is also used for gastric protection to prevent the recurrence of stomach ulcers or gastric damage from the chronic use of NSAIDs. Pantoprazole sodium is also used to treat Zollinger-Ellison syndrome and other conditions involving excess stomach acid. Pantoprazole sodium is advised as a prescription product as well as the generic prescription product. Manufacturers market Pantoprazole under the Brand name of Protonix, Protonix I.V., Panto IV, Somac Control. Pantoprazole Sodium is available in the dosage form of Tablet (delayed-release), Injection (powder for solution), and Oral Suspension. The tablet and suspension form is administered orally and the injection is administered Intravenously. Pantoprazole is available in 20 mg and 40 mg dosage strengths. Tablets should be swallowed whole and can be taken with or without food. If patients are unable to swallow 40 mg tablets, two 20 mg tablets may be taken, but 40 mg oral suspension should not be divided into two 20 mg dosage for pediatric patients who are unable to take tablet formulation. The usual recommended adult dose for GERD is 40 mg pantoprazole tablet given once a day orally for a duration of 8 weeks or 40 mg I.V. injection administered once a day for a duration of 7-10 days. For Zollinger-Ellison syndrome, the recommended dose is 40 mg tablet orally twice a day or 80 mg I.V. injection administered every 12 hours with a maximum dose of 240 mg/day for a maximum duration of 6 days. The recommended storage conditions for pantoprazole sodium tablets and I.V. infusion is to store at 20° C to 25° C (68° F - 77° F) with excursions permitted to 15° C to 30° C (59° F - 86° F), protect from sunlight. The reconstituted product should not be frozen.

Wholesale Price of Pantoprazole Sodium

In the USA, the wholesale price of 20 mg pantoprazole oral delayed-release tablets ranges from $ 36.84 - $ 159.46 for a quantity of 90 tablets and the per-unit cost is available at as low as $ 0.41 The per-unit cost of 40 mg pantoprazole oral delayed-release tablet ranges from $ 0.40 - $0.94 and for a quantity of 90 tablets, the cost ranges from $ 36.84 - $ 84.62 The wholesale price of 40 mg pantoprazole intravenous powder for injection costs around $ 38.06 - $ 69.00 for a quantity of 10 and the per-unit cost ranges from $ 3.81 - $ 6.90

Pantoprazole Sodium - Mechanism of Action

Pantoprazole Sodium suppresses gastric acid secretion by inhibiting the partial cell membrane H+ K+ ATPase enzyme system. This effect leads to inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus. The binding to the H+, K+ ATPase results in a duration of antisecretory effect that persists longer than 24 hours.

Finding Pantoprazole Sodium Manufacturers and Suppliers

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