Pazopanib Hydrochloride belongs to the class of drug called “Kinase inhibitor”. It is sold under the trade name “Votrient” and is marketed by Novartis. It is indicated for the treatment of renal cell sarcoma, ovarian cancer, and non-small cell lung cancer. It can also be used to treat advanced soft tissue sarcoma (STS) and advanced thyroid cancer. It is taken through the oral route on an empty stomach. It is primarily excreted in feces and 4% in urine. This drug can interact with certain drugs which include Irinotecan, aspirin, and warfarin. Hepatotoxicity, as manifested by increases in alanine aminotransferase (ALT), aspartate aminotransferase (AST), and bilirubin, has been observed in patients receiving Pazopanib Hydrochloride. This hepatotoxicity can be serious and fatal. Side effects associated with this pharmaceutical medicine include changes in hair color, hypertension, hyperglycemia, hypoglycemia, hypocalcemia, hypomagnesemia, hypophosphatemia, laboratory test abnormalities, edema, abdominal pain, fatigue, and bone marrow suppression. Its use should be avoided during pregnancy. The FDA has not yet assigned any category to this pharmaceutical medicine during pregnancy. For lactating women, its use should be avoided. No data is present regarding its excretion into milk. It was approved by the FDA on 26th April 2012.

It works by its antiangiogenic properties by inhibiting intracellular tyrosine kinase of VEGE receptor and PDGF receptor.

For a supply of 120 tablets of Pazopanib Hydrochloride oral tablets 200mg, it costs around $15,207. Prices may fluctuate from seller to seller.

A global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. Therefore, the list of Pazopanib Hydrochloride offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you find the countries that manufacture this pharmaceutical substance. These also enable you to check the dossier status of this medicine, and the GMP approvals of the different variants of Pazopanib Hydrochloride Moreover, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Pazopanib Hydrochloride is already registered in. It is important to note that these manufacturers may have special delivery terms.

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