Tolperisone:

Tolperisone, also known by its popular brand name Mydocalm, is a centrally acting skeletal muscle relaxant used as a medication in the treatment of increased muscle tone associated with neurological diseases. It is sold under brand names including Mydocalm, Biocalm, Mydeton, Miderizone, Mydoflex, Myolax, Myoxan and Viveo. It has been commonplace in the global medical marketplace since the 1960s when it was approved for use. Currently, it has entered the generic drugs space allowing for tolperisone manufacturers and tolperisone suppliers to list it for sale in a cost-efficient manner. Where it can often be found available to order on the wholesale pharmaceutical products list of global distributors, at a variety of cost and price points.

Mechanism of action of tolperisone:

Tolperisone belongs to a group of pharmaceutical products derived from piperidine. Its precise mechanism of action remains elusive, however, it is known to block both sodium and calcium ion channels. This impedes nervous transduction and muscle activation. It has a high affinity for nervous system tissue, reaching the highest concentrations in the brain stem, spinal cord, and peripheral nerves. Where it functions as a centrally acting muscle relaxant. Additionally, studies have shown that it has non-sedative properties and no interactions with alcohol.

Form and dosage of tolperisone:

The final form and packaging are dependent on the manufacturers and suppliers, as well as the specific distributors and order. However, tolperisone is frequently listed for wholesale in forms including tablets, solution for injection, solution for infusion, and film-coated tablets. For those under 6 years of age 5mg/kg daily is recommended, with those between 6-14 years of age requiring 2-4mg/kg, and adults needing 150-450mg/kg orally. For those with hepatic impairment, special care should be taken by the healthcare provider and the patients’ hepatic function closely monitored. Adverse side effects are uncommon, occurring in fewer than 1% of patients and include muscle weakness, headache, arterial hypotension, nausea, vomiting, dyspepsia, and dry mouth. For a complete list and further information please refer to the manufacturers’ literature.

Tolperisone on Pipelinepharma:

Currently, at the time of writing, we have found 7 verified tolperisone manufacturers and tolperisone suppliers from our online global list of B2B sellers. These manufacturers, suppliers, and distributors are located in various countries including Thailand, Ukraine, European Union, Belarus, and Taiwan. Each company and their pharmaceutical products list listed on our online B2B platform has been verified by the Pipelinepharma team. This ensures seller reputability while reducing souring mileage and dead ends, allowing for a hassle-free buying experience.

Price of tolperisone and how to buy:

A search through our online B2B platform reveals a cost of approximately USD 7.4 for 50mg x 50 tablets of tolperisone. As with all drugs, however, the specific cost will be highly dependent on the individual buyer, manufacturers, quantity, and market. Therefore the price indicated above solely serves as generalizations of the current market pricing. To purchase tolperisone through our pharmaceutical products marketplace, simply search for the desired product, choose a listing, and select either ‘Accept’, ‘Negotiate’, or ‘Get offer’ through the displayed embedded buttons. Onscreen instructions will then guide you through the process.