terbinafine hydrochloride Cream 1 %

Terbinafine Hydrochloride is available under the brand name “Lamisil”. It belongs to the drug class of antifungal drugs. It is indicated for the treatment of skin infections which includes athlete’s foot, fungal nail infections, ringworm, jock itch, and pityriasis Versicolor. It can be administered through the oral route in the form of tablets or granules taken with soft food. Drugs that interact with this pharmaceutical medicine include warfarin, amiodarone, famotidine, rifampin, azole antifungals, tricyclic antidepressants, and many others. Only apply this medication topically. Make sure the treatment area is clean and dried completely before you begin. Once or twice daily, as instructed on the product label, apply a thin layer of the medication on and around the affected area. After use, wash your hands thoroughly unless the treatment area also includes your hands. Side effects associated with this pharmaceutical medicine include diarrhea, change or loss of smell and taste, vision changes, mental/mood changes, depression, bleeding/bruising, unusual tiredness, and kidney problems such as a change in urine frequency. It is contraindicated in conditions like depression, liver problems, systemic lupus erythematosus, abnormal liver function tests, and a drop in neutrophil count. It has been assigned as category B by the FDA. It is secreted in human milk in small amounts. If a 500mg oral dose is taken, only 0.65mg or 0.15mg will be excreted into milk which is 0.13% and 0.03% respectively. Its topical use on the breast should be avoided. It was approved by the FDA on 28th September 2007, under the brand name Lamisil manufactured by Novartis Pharmaceutical Corporation.

It has the fungicidal effect which is executed by inhibition of enzyme squalene monooxygenase, which in turn inhibits sterol biosynthesis of fungus by decreasing its ergosterol levels.

For a supply of 30 tablets of Terbinafine Hydrochloride oral tablets, 250mg it costs approximately $67.59.

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