Agomelatine is an antidepressant that is used to treat serious depression. According to one study, it is equally effective as other antidepressants, with broadly similar discontinuation rates but fewer due to side effects. Another study indicated that it was as effective as several other antidepressants. Weight gain, exhaustion, liver issues, nausea, migraines, and anxiety are all common adverse effects. Blood tests should be done on a regular basis because of the possibility of liver issues. It is not advised for those with dementia or those over the age of 75. It appears to have minimal side effects than certain other antidepressants, according to preliminary studies. Melatonin receptors are stimulated, while serotonin receptors are blocked. In healthy volunteers, agomelatine has no effect on daytime vigilance or memory. Treatment with the medicine boosted slow-wave sleep in depressed patients without affecting the amount of REM (Rapid Eye Movement) sleep or REM latency. Agomelatine also caused an earlier beginning of sleep and a lower minimum heart rate. Patients reported that the beginning of sleep and the quality of sleep increased dramatically during the first week of medication, with no daytime clumsiness.

Agomelatine binds to melatonin and acts as a melatonin agonist. It works by resetting the sleep-wake cycle, which is disrupted in those who are depressed. Agomelatine's active ingredient is an antidepressant. It acts by activating the MT1 and MT2 receptors in the brain and inhibiting the 5-HT2C receptors. The neurotransmitters dopamine and noradrenaline are considered to arise as a result of this.

An online search for the wholesale price for sale of Agomelatine for distributors will reveal a wide range of costs. It will vary from store to store depending on your visit and the country of the wholesale market.

Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Agomelatine distributors offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for these substance manufacturers and this substance Agomelatine suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Agomelatine. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Agomelatine is already registered in. Manufacturers also have special, and delivery terms.

If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical product deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the manufacturers Agomelatine suppliers. This way, the marketplace allows you as a distributor to skip the process of shortlisting product manufacturers every time you are looking for in-licensing or distribution deals.

To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are onboarded on the platform. This allows us to screen Agomelatine Manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.