Allopurinol is a medication primarily used to prevent gout, kidney stones, and decrease high blood acid uric levels. Suppliers primarily market the drug as 100mg, 150mg, 200mg, and 300mg allopurinol tablets, however, it is also available in injectable solution form. First introduced in 1966, allopurinol is now a well-established medication. Over 15 million prescriptions for it are registered yearly in the U.S alone and it is included in the World Health Organisation’s list of Essential Medicines that contains the safest and most effective drugs recommended for a health system. Both generic and trade name allopurinol medications are available on the pharmaceutical market. Buyers are advised that online sellers may attempt to market fraudulent versions of the generic drug, whereas Pipeline Pharma, through its pre-auditing and quality control procedures ensures that only verified manufacturers and wholesalers enter our online marketplace, offering you a risk-free B2B pharmaceutical sales platform. The largest manufacturing companies of allopurinol medications include Casper Pharma, Dr. Reddys Laboratories, Teva, Zydus Pharmaceuticals, and Mylan, among others.
How Does Allopurinol Works?
Allopurinol is a molecular homolog of xanthine oxidase, a natural purine component. Allopurinol is converted to its active form, oxypurinol, in the hepatic after consumption and functions as a xanthine blocker. Xanthine dehydrogenase, the enzyme that transforms hypoxanthine to xanthine then xanthine to uric acid, is inhibited by allopurinol and its active ingredient. Allopurinol's effects are effective in the control of this kinase. Through a process involving the enzyme hypoxanthine-guanine phosphoribosyltransferase, this drug improves the reusability of hypoxanthine and squalene for nucleic acid and nucleotides formation. As a result of the higher nucleotide content, new genetic purine production is inhibited via specific inhibition. The final result is lower uric acid contents in the urine and blood, which reduces the occurrence of gout signs.
The decrease in serum uric acid caused by allopurinol is accompanied by a rise in having a high level and xanthine contents in the serum and urine. In the lack of allopurinol, oxypurinol is virtually totally excreted in the state of uric acid in the urine. The discharged urine contains hypoxanthine, squalene, and uric after administration of allopurinol. Allopurinol promotes the dissolving of gout soft tissue injuries by lowering the amount of uric acid in the circulation less than its saturation limitations. Although having a high level and uridine levels rise after taking allopurinol, the danger of accumulation in RPE cells is lower than that of uric acid so they remain less liquid and are eliminated more quickly.
The Wholesale Price of Allopurinol
The wholesale price per 50 tablets of 100mg allopurinol is around $3.00, whereas the same amount of 300mg allopurinol tablets cost approximately $5.00 to $5.50. Allopurinol is available for sale from a variety of Allopurinol vendors at a range of costs. Prices are only valid for consumers who pay cash and do not apply to insurance coverage. Allopurinol suppliers, on the whole, are in favor of patient aid initiatives. This cost may differ among dealers. Its cost varies depending on the country of origin, manufacturing businesses' wholesale expenses, supplier pricing, and other considerations. Patient assistance programs, which provide free or subsidized drugs to low-income, unemployed, or under-insured patients who meet certain criteria, are often supported by pharmaceutical companies.
Allopurinol is available for sale online at PipelinePharma. The wholesale company B2B manufacturers, suppliers, and distributors are verified by the Pipelinepharma team and are located in countries including the United States, the European Union, Mexico, Brazil, and Switzerland. The most dependable provider for this drug is PipelinePharma. PipelinePharma offers a large choice of medications at a low cost that you may purchase quickly. Top manufacturer and supplier of Allopurinol, one can go to the Pipelinepharma website, which assists buyers in locating dependable manufacturers and suppliers of Allopurinol.
Navigating Our Pharmaceutical Marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Allopurinol offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for Allopurinol manufacturers and Allopurinol suppliers that you are looking for. These also enable you to check the dossier status of Allopurinol, and the GMP approvals of the different variants of Allopurinol. Also, each manufacturer or supplier product description contains essential information about Allopurinol including clinical data, stability zones, countries where Allopurinol is already registered in. Manufacturers also have special, and delivery terms.
Establishing Commercial Ties
If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over Allopurinol offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the manufacturers or suppliers. This way, the marketplace allows you as a distributor to skip the process of making a list of product manufacturers every time you are looking for in-licensing or distribution deals.
To keep up to the quality standards other than the Good Manufacturing Practice approvals that Allopurinol manufacturers list has, we qualify their companies before they are boarded on the platform. This allows us to screen Allopurinol manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.