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Apixaban manufacturers

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Country of origin : Brazil

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apixaban

Tablets 2.5 mg, 5 mg

Dossier type
CTD
Dossier status
Ready to file
Country of origin
Brazil
GMP approvals
ANVISA
Manufacturer #34253

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Apixaban Manufacturers

Apixaban is an anticoagulant that is classified as a Factor Xa inhibitor and is commonly marketed as Eliquis. It works by acting upon and inhibiting Factor Xa in the coagulation cascade and thus preventing clot formation. This pharmaceutical medicine is primarily used to prevent stroke in patients with atrial fibrillation. Furthermore, it is used post-operatively after hip and knee surgery to prevent the risk of Deep Venous Thrombosis (DVT) and in extension Pulmonary Embolism (PE). It is also used to treat both these conditions, and for secondary prevention after the first attack has occurred. Apixaban is strictly prohibited if the patient has an active bleeding disorder, liver disease, renal disease, or Anti-phospholipid antibody syndrome. Moreover, this pharmaceutical remedy should not be administered if the patient has a history of hypersensitivity to the drug or its constituents, or if the patient has prosthetic heart valves. There are certain side effects that need to be looked out for while taking this pharmaceutical medicine. They include allergic reactions, skin rash, fainting spells, and nausea. The ones that warrant immediate attention are easy bruising, heavy menses, dizziness, headache, bleeding from unusual sites, prolonged bleeding, brown urine, bloody stools, and numbness or restricted movement of the limbs. Apixaban is available for oral administration in the form of tablets. It has to be taken twice a day with or without food. It is available in two doses: 2.5 mg and 5 mg. Apixaban was approved by the Food and Drug Administration (FDA) for use after hip and knee surgery on March 18, 2014, and for treatment and prevention of DVT And PE on August 21, 2014. This pharmaceutical medicine is not approved for use during pregnancy or lactation.

How does Apixaban Work?

It works by thinning the blood, thereby reducing the chances of clot formation. Apixaban suppresses factor Xa in both it is free and post-processed, regardless of the presence of antithrombin IIILabel. ProthrominaseLabel is also inhibited by apixaban. The creation of a thrombus is prevented by these effects. Apixaban is used to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation, as well as for the prevention of deep vein thrombosis (DVT) leading to pulmonary embolism (PE) in patients who have had hip or knee replacement surgery, and for the treatment of DVT and PE to prevent a recurrence. Apixaban is an inhibitor used to prevent stroke and systemic embolism in individuals with nonvalvular atrial fibrillation, as well as deep vein thrombosis (DVT) leading to pulmonary embolism (PE) in people who have had hip or knee replacement surgery. Apixaban is an antithrombin III-independent, oral, direct, and highly selective factor Xa inhibitor that inhibits both free and bound FXa, as well as prothrombinase, for the treatment and prevention of thromboembolic disorders. Eliquis is the brand name for it. On December 28, 2012, the FDA authorized apixaban.

The Wholesale Price of Apixaban

Apixaban can be purchased from any drugstore. A month's supply of Apixaban costs $450-500 in the US, whereas in Europe it costs 80 EUR both for the 2.5mg and the 5mg tablets. The prices may vary highly as per the location of the pharmacy. But the prices may vary widely as per the pharmacy or drugstore location you visit. Wholesale price differs according to the wholesaler of the region or country where the order has been processed for sale. Prices are only valid for cash-paying consumers and do not apply to insurance schemes. Pharmaceutical corporations generally support patient assistance programs (PAPs), which provide free or subsidized drugs to low-income, unemployed, or under-insured individuals who meet certain criteria. Some offers can be downloaded directly from a website, while others need registration, completion of a survey, or the collection of a sample from a physician's office.

Navigating Our Pharmaceutical Marketplace

Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Apixaban offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for these Apixaban manufacturers and these Apixaban suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Apixaban. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Apixaban is already registered in. Manufacturers also have special, and delivery terms.

Establishing Commercial Ties

If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and ordering process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the Apixaban manufacturers or Apixaban suppliers. This way, the marketplace allows you as a distributor to skip the process of shortlisting product manufacturers every time you are looking for in-licensing or distribution deals.

Quality Assurance

To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are onboarded on the platform. This allows us to screen Apixaban manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.

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