Doxorubicin Manufacturers
Doxorubicin is a cytotoxic and anthracycline chemotherapy drug belongs to a class of drugs called Anthracyclines. It is an antineoplastic antibiotic obtained from Streptomyces peucetius. Doxorubicin is used alone or in combination with other medications to treat several different types of cancers like, cancers of the thyroid, stomach, small cell lung cancer, liver, squamous cell cancer of head, neck, ovary, breast and prostate.
This medication is advised as a prescription product and generic prescription product and before using this medication, the risk of taking the drug must be weighed against the benefits it provides. Doxorubicin should be given only under medical supervision with experience in the use of chemotherapy medications.
Manufacturers of Doxorubicin market these drugs under the Brand name of Caelyx, Adriamycin, Doxil. This drug is available in an injectable dosage form (powder for solution, suspension) in 2 mg/mL, 10 mg, 20 mg/1, 50 mg/1, 75 mg, 100 mg and 150 mg/1 dosage strengths. These injections are supplied in polypropylene vials in a single vial pack for single dose use and for multiple dose use. This medication is administered through an intravenous route and is usually given once every 21 to 28 days and the duration of the treatment depends on the patient’s response and the type of cancer. The recommended dose of doxorubicin in patients with adjuvant breast cancer is 60 mg/m2 administered as I.V bolus in combination with cyclophosphamide on day 1 of each 21-day treatment cycle for a total of 4 cycles.
In patients with ovarian cancer, the initial recommended dose is 50 mg/m2 administered at a rate of 1 mg/min to minimize the risk of infusion reactions, if no infusion related reactions are found, the rate of infusion can be increased to complete administration for over one hour once every 21 day. Doxorubicin vials are stored at 2° C to 8° C (36° F - 46° F) with protection from light.
How does Doxorubicin work?
Doxorubicin is an anthracycline antibiotic which works by slowing or stopping the growth of cancer cells. Doxorubicin has both antimitotic and cytotoxic activity. This drug forms complexes with DNA by intercalation between base pairs and this intercalation inhibits nucleotide replication and action of DNA and RNA polymerases which results in inhibition of topoisomerase II activity (replication and transcription) by stabilizing the DNA-topoisomerase complex. The intercalation of doxorubicin with topoisomerase II to form DNA complex is the most important mechanism of doxorubicin cytocidal activity.
The Cost of Doxorubicin
An online search for the wholesale price for sale of Doxorubicin for distributors will reveal a wide range of costs. It will vary from store to store depending on your visit and the country of the wholesale market. The wholesale price of doxorubicin 2 mg/ml intravenous solution comes at $ 17.06 for a supply of 5 milliliters with per unit cost available at $ 3.41 The cost for doxorubicin intravenous solution is around $ 26.30 for a supply of 10 milliliters with per unit cost available for as low as $ 2.63, while for 25 milliliters it costs approximately $ 29.12 The cost for doxorubicin intravenous solution is around $ 64 for a supply of 100 milliliters with per unit cost available for as low as $ 0.64
Navigating our pharmaceutical marketplace
Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Doxorubicin distributors offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for these substance manufacturers and this substance Doxorubicin suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Doxorubicin. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Doxorubicin is already registered in. Manufacturers also have special, and delivery terms.
Establishing commercial ties
If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical product deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and order process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the manufacturers Doxorubicin suppliers. This way, the marketplace allows you as a distributor to skip the process of shortlisting product manufacturers every time you are looking for in-licensing or distribution deals.
Quality Assurance
To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are onboarded on the platform. This allows us to screen Doxorubicin Manufacturers for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.
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