Lomefloxacin Hydrochloride is a pharmaceutical drug that is sold under the brand names Lomebact, Lomed, Lomecin, and Maxaquin, and is classified under the drug class Fluoroquinolone antibiotics. Being a broad-spectrum anti-biotic, this pharmaceutical product is indicated for the treatment of various anti-bacterial infections such as bronchitis and urinary tract infections. This pharmaceutical medicine is commonly administered through the oral route in the form of a tablet. It is advised for the patient to take extra water than normal while using this drug to avoid crystal formation in the urine. It has drug interactions with antacids containing aluminum or magnesium, ulcer medicine sucralfate, and vitamin or mineral supplements containing iron or zinc. Common side effects include seizures, confusion, hallucinations, liver damage, muscle pain or joint pain, diarrhea, lightheadedness, increased skin sensitivity to sunlight. This pharmaceutical medication is not recommended for children below the age of 12 years as it may affect bone development. It is contraindicated in patients having kidney diseases and seizures or epilepsy, but dose adjustments may prove helpful in such conditions. The FDA has categorized it in category C of pregnancy-safe drugs and can only be used with the recommendation of your doctor. Its secretion into human breastmilk is not yet evidenced and hence cannot be taken without doctors’ consultation in lactating women. The FDA approved it on February 21, 1992, under the brand name Maxaquin for the strength 400mg and dosage form oral tablet, manufactured by Pharmacia.

It interferes with the activity of DNA Gyrase and Topoisomerase 4 thus influencing the bactericidal action.

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