Methylphenidate falls under the drug class of CNS Stimulants. It is commonly marketed as Ritalin. This pharmaceutical remedy is used to treat diseases such as Attention Deficit Hyperactive Disorder (ADHD) and Narcolepsy, owing to its property of preventing the reuptake of certain neurotransmitters in the brain. Furthermore, it may also be used to treat resistant cases of depression and bipolar disorder. Methylphenidate should be strictly avoided in individuals who are on the treatment regimen of Monoamine Oxidase Inhibitors (MAOs), those who are diagnosed with tics or glaucoma, or if there is a previous or current history of allergic reaction to this pharmaceutical medicine. This pharmaceutical remedy is available in the form of a simple tablet, chewable tablet, capsule, liquid solution, and transdermal patch. The tablets and capsules can be taken as either an immediate release or extended release. Despite the merits, this pharmaceutical medicine may cause certain adverse effects, which include loss of appetite, xerostomia, anxiety, nausea, insomnia, abdominal pain, dizziness, change in blood pressure, tachycardia, blurred or double vision. A hypersensitivity reaction may also occur with a clinical presentation of skin rash and fever and is more commonly seen with the use of the transdermal patch. Very rarely, changes in libido, hallucinations, and priapism have also been reported. The use of Methylphenidate for the treatment of ADHD in children over the age of 6 was approved by the US Food and Drug Administration (FDA) in 1955. The use of this pharmaceutical remedy during pregnancy should only be advised if the benefits outweigh the risks, as there is a lack of studies on human subjects regarding the benefits of this drug. Whereas, it can be used during lactation, as no adverse effects have been reported in infants of such mothers, however, continuous monitoring for danger signs is advised.

The per-unit cost is $0.78, whereas a pack of 100 tablets costs $78.08.

This pharmaceutical remedy works by increasing the transit time of neurotransmitters like Dopamine and Noradrenaline in the synaptic cleft (the space where two neurons meet) by blocking their re-uptake. Since these transmitters appear to be depleted in Depression and ADHD, this helps in controlling symptoms.

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