Pegfilgrastim is a form of protein used to stimulate the growth of "healthy" white blood cells in the bone marrow, once chemotherapy is given. White blood cells help the body fight infection. This is not a chemotherapy drug. It can also be used to stimulate the bone to produce more marrow and neutrophils to fight infection in patients receiving chemotherapy.
Pegfilgrastim manufactures and suppliers market it under several brand names, including Neulasta among others.
Pegfilgrastim was first developed by Amgen in 2002 was approved by FDA for use in the same year, in the same year, it was also approved for sale in the European continent.
Dosage
This medication is normally administered at least 24 hours after chemotherapy. It’s job is to stimulate the growth of new white blood cells. Pegfilgrastim is administered as a single injection. The injection can be given subcutaneously in pre-filled syringes. The dose is dictated by the ailment of the patients and condition.
Cost of Pegfilgrastim
The list price for Neulasta®, the most popular brand, is $8,500 per dose in the USA. Whereas in the UK, the Price for 6mg/0.6ml in a Pre-filled syringe is £411.83.
How does it work?
Chemotherapy and radiation therapy put a patient at risk for developing infections, anemia, and bleeding problems. The body's bone marrow produced blood cells of three major types. White blood cells for fighting infection. The Red blood cells carry oxygen to and remove waste products from organs and tissues, and the platelets, which enable blood clotting. Factors are substances that stimulate the body to create blood cells and boost their ability to function. The role of Pegfilgrastim is in stimulating blood cells, as they are the patient’s immune system during chemotherapy.Finding Pegfilgrastim Manufacturers and Pegfilgrastim Suppliers
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Brand Names:
Fulphila, Neulasta, Neulasta Onpro Kit, Udenyca, Ziextenzo
Packagers:
Amgen Inc., Physicians Total Care Inc
Main companies:
Amgen Inc, Harbin Pharm, Qilu Pharmaceutical, SL PHARM, Amoytop Bio, Hexal, Kirin Kunpeng (China) Bio-Pharmaceutical Co., Ltd., Chugai Pharmaceutical Co., Ltd., Novartis International AG, Pfizer Inc., Teva Pharmaceutical Industries Ltd, Dr. Reddys Laboratories, BIOCAD, Hospira, Intas Pharmaceuticals Limited, GenSci, Merck Group
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