Metolazone
Metolazone is a medication called ‘water pills’, belonging to a type of drugs called diuretics,
primarily used to treat congestive heart failure and high blood pressure. Lowering high
blood pressure helps in the prevention of serious heart and kidney problems. Metolazone helps
in reducing the swelling and fluid retention in cases patients with heart failure and or kidney
disease. Metolazone makes kidneys decrease the amount of water and salt it stores body by
increasing the amount of urine, as in its primary action while treating kidney problems is
make the body produce more urine to order expel the excess fluids. Metolazone is frequently
a part of larger combination of therapy.
Metolazone is marketed under the brand names Zytanix, Metoz, Zaroxolyn, and Mykrox to
name a few.
Metolazone was first patented in 1966 and later developed in the 1970s, by an Indian born
chemist Dr. Bola Vithal Shetty. Metolazone gained popularity it causes little kidney toxicity
compared to other diuretics. It has been approved for medical use since 1974.
Forms and Dosage
Metolazone is sold as tablets in the increasing strength of 2.5mg, 5mg, and 10mg tablets. For
the treatment of edema in congestive heart failure or kidney disease, a dose of 5-20mg once
daily, as the initial treatment. The dosage is adjusted as per the response of the body. In the
treatment of high blood pressure, the patients are administered 2.5-10 mg once a day.
Metolazone should not be taken at the start of the day or activity, because it takes some time
for its absorption and duration of action.
The Cost of Metolazone
The cost of 30 tablets of 5 mg strength will cost the consumer a retail price of USD65 on a
average, it is as low as USD56 and as high as USD75 based on the brand and pharmacy in the
USA. In the UK, the same supply from the generic drug maker cost upwards of 15 pounds.
How does Metolazone work?
Metolazone works by increasing the amount of urine body makes, in the process making the
body get rid of excess fluids/liquids through the urine. Metolazone indirectly decreases the
amount of water getting reabsorbed into the bloodstream through the kidney, there by
decreasing the blood volume and increasing the urine volume. As the body expels the salts in
urine, it helps lowering the blood pressure and preventing excess fluid accumulation during
heart failure.
Finding Metolazone Manufacturers and Metolazone Suppliers
One of the fastest and easiest ways to find Metolazone manufacturers and Metolazone
suppliers is to make use of Pipelinepharma's global B2B online marketplace for medicines
and other pharmaceuticals.
Usually, finding trusted manufacturers and supplies of specific drugs like Metolazone can be
a time-consuming challenge, but with Pipelinepharma's simple search engine and network of
proven partners, the whole process becomes a lot easier.
All you need to do to get started is to make use of our integrated search engine and start looking
for suppliers or manufacturers of Metolazone to work with. You can fine-tune your search
results using various filters too, letting you search for Metolazone from specific countries, for
example.
https://en.wikipedia.org/wiki/Metolazone#:~:text=Metolazone%20is%20a%20thiazide%2Dli
ke,failure%20and%20high%20blood%20pressure .
https://medlineplus.gov/druginfo/meds/a682345.html
https://medlineplus.gov/druginfo/meds/a682345.html
https://www.webmd.com/drugs/2/drug-8431/metolazone-oral/details
https://www.ncbi.nlm.nih.gov/books/NBK534203/
https://pubchem.ncbi.nlm.nih.gov/compound/Metolazone
https://reference.medscape.com/drug/zaroxolyn-metolazone-342416
https://www.drugbank.ca/drugs/DB00524
https://www.healthline.com/health/metolazone-oral-tablet