Oxycodone hydrochloride is the hydrochloric salt of oxycodone - an opioid class drug that is used to treat mild to severe pain. The drug is primarily marketed as immediate-release as well as controlled-release oxycodone hydrochloride tablets, but also in the forms of capsules, oral solutions, and solutions for injection. Oxycodone is available as a standalone medication and as an ingredient in combination drug formulations (along with acetaminophen, aspirin, ibuprofen, naloxone, or naltrexone). Marketed as both generic and trade name medications, it is among the most popular prescription drugs, accounting for over 14 million prescriptions yearly in the U.S. alone. The largest manufacturers of oxycodone hydrochloride include Mallinckrodt, Purdue Pharma, and Noramco, while notable suppliers of the drug are Sanofi-Aventis, Johnson & Johnson, and Pfizer. Opioids are among the most effective pain-relief medications, especially in cases of severe pain, and their use is common practice in most countries. However, due to the side effects and dependency risks associated with opioid drugs, the sale of oxycodone hydrochloride is prohibited in certain countries. Also, other countries may have national laws that limit the export, import, distribution, or commercialization of oxycodone.

It is unknown how exactly oxycodone works. Opioid receptors are increased and delivered to nerve terminals in the heart, lungs, brain, gastrointestinal tract, and reproductive system when there is inflammation or hyperalgesia. Opioid agonists include oxycodone and its bioactive metabolites noroxycodone, oxymorphone, and noroxymorphone. The blood brain barrier is either passively crossed by these substances or it may be actively crossed by an unidentified mechanism. In the peripheral and central nervous systems, oxycodone and its active metabolites can preferentially bind to the mu opioid receptor while also activating the kappa and delta opioid receptors. When mu opioid receptors are activated, N-type voltage-operated calcium channels are blocked, which blocks pain perception. Noroxycodone is produced from oxycodone by CYP3A4 and CYP3A5, which is subsequently converted to noroxymorphone by CYP2D6. 1 The two main metabolites in circulation are noroxycodone and noroxymorphone. Label As alpha or beta noroxycodol, noroxycodone can also be 6-keto-reduced. By way of CYP2D6 and CYP3A4, oxycodone can be converted to oxymorphone and then noroxymorphone. Alpha- or beta-oxymorphol can be produced from oxymorphone by 6-keto-reduction.

Retail prices per 30 5mg oxycodone hydrochloride tablets are around 7 EUR, while the equivalent amount of 10mg tablets costs approximately 12 EUR. Also, the costs of Oxycodone Hydrochloride vary depending on manufacturer and supplier pricing, whether it is a generic or trade name formulation, concentration of the active ingredient in the formulation. It is available for sale at every medical store. Oxycodone Hydrochloride suppliers, on the whole, are in favor of patient aid initiatives. Oxycodone Hydrochloride is available for sale from various Oxycodone Hydrochloride vendors at multiple costs.

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Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Oxycodone Hydrochloride offerings can be narrowed down with filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for this substance manufacturer and Oxycodone Hydrochloride suppliers that you are looking for. These also enable you to check the dossier status of this medicine and the GMP approvals of the different variants of Oxycodone Hydrochloride. Also, each manufacturer or supplier product description contains essential information about this substance, including clinical data, stability zones, and countries in which Oxycodone Hydrochloride is already registered. Manufacturers also have special delivery terms.

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