Paracetamol manufacturers

What is Paracetamol?

Paracetamol, also known as acetaminophen, is a common over-the-counter pain reliever and fever reducer. Paracetamol belongs to the class of medications known as analgesics and antipyretics, which work by blocking the production of specific chemicals in the body that causes pain and fever.

Paracetamol is used to treat mild to moderate pain, such as headaches, toothaches, menstrual cramps, and muscle aches. It can also be used to reduce fever associated with infections, such as the flu or colds.

Paracetamol is available in various forms, including tablets, capsules, liquid suspensions, and suppositories. It is generally considered safe when used as directed, but excessive use or overdose can cause liver damage and other serious health problems.

Paracetamol forms and dosage

Paracetamol is available in several forms and dosages, including:

1. Tablets or capsules: Paracetamol tablets or capsules are available in strengths of 325 mg, 500 mg, and 650 mg. The recommended dosage for adults is usually 325 mg to 1000 mg every 4-6 hours, with a maximum daily dose of 4000 mg.
2. Liquid suspensions: Paracetamol liquid suspensions are often used for children and come in different strengths and flavours. The recommended dosage for children depends on their age and weight and is usually between 10mg/kg to 15mg/kg, given every 4-6 hours.
3. Suppositories: Paracetamol suppositories are another option for people who cannot swallow tablets or capsules. They are available in strengths of 80 mg to 500 mg and are typically used for children.

Paracetamol patent information

Paracetamol, also known as acetaminophen, was first synthesized in 1878 and has been available as a generic drug for many years. The original patent for Paracetamol expired in 1951, meaning that the drug can now be produced and sold by any manufacturer without needing a license from the original patent holder.

However, some companies have patented specific formulations or combinations of Paracetamol with other drugs. For example, GlaxoSmithKline (GSK) holds patents for various combinations of Paracetamol with other drugs, such as codeine or caffeine, which are used to treat pain and headaches.

Paracetamol wholesale price

In general, the wholesale price of Paracetamol is relatively low and affordable in most countries, particularly in countries where it is widely produced and distributed. The price may vary depending on the local market conditions, import and export regulations, and other factors such as transportation and storage costs.

Paracetamol API reference price is around 6 USD/kg.

Paracetamol manufacturers and brands

Some of the most well-known paracetamol manufacturers and brands include:

1. Johnson & Johnson produces Paracetamol under the brand name Tylenol.
2. GlaxoSmithKline produces Paracetamol in combination with other substances, such as Codeine, under the brand name Panadol.
3. Perrigo is a pharmaceutical company that produces a range of generic drugs, including Paracetamol, under the brand name of various retail chains, such as Walmart's Equate brand and Walgreens' Nice! brand.
4. Teva Pharmaceutical Industries is producing a range of generic drugs, including Paracetamol, under the name Teva.
5. Novartis produces a range of medications, including Paracetamol, under the brand name Excedrin.

Paracetamol is produced by many manufacturers and, thus, has many brand names. Among them, we can list Tylenol, Panadol, Acamol by Teva, Acetalgin, Actamin, Algotropyl, Alvedon, Banesin, Calpol, Conacetol, Dafalgan, Disprol, Dolprone, Dymadon, Enelfa, Febridol, Gelocatil, Genapap, Genebs, Injectapap, Liquiprin, Napafen, Paldesic, Panofen, Paraspen, Redutemp, Rounox, Salzone, Suppap, Tapanol, Valorin. Paracetamol suppliers market it in various final dosage forms, such as 80 mg, 160 mg dispersible tablets, 80 mg, 160 mg, 500 mg chewable tablets, 325 mg, 500 mg tablets, 650 mg extended-release tablets, 160 mg/5 ml syrup, 325 mg, 500 mg capsules, 10 mg/1 ml solution for injections, 325 mg suppositories.

Paracetamol in combination with other substances

Paracetamol is commonly combined with other substances to enhance its pain-relieving or fever-reducing effects. Some of the most popular Paracetamol combinations with other substances include:

1. Paracetamol + Codeine: This combination is often used to treat moderate to severe pain caused by dental procedures or surgery. The codeine works by enhancing the pain-relieving effects of Paracetamol.
2. Paracetamol + Caffeine: This combination is often used to treat headaches and migraines. Caffeine works by constricting blood vessels in the brain, which can help to relieve headache pain.
3. Paracetamol + Diphenhydramine: This combination is often used to treat pain and fever associated with cold and flu symptoms. Diphenhydramine is an antihistamine that can help to reduce fever and relieve pain.
4. Paracetamol + Ibuprofen: This combination is sometimes used to treat adult pain and fever. Ibuprofen is a nonsteroidal anti-inflammatory drug that reduces inflammation and relieves pain.
5. Paracetamol + Oxycodone: This combination is often used to treat severe pain caused by cancer or surgery. Oxycodone is an opioid that binds to opioid receptors in the brain and spinal cord to relieve pain.

Connecting to Paracetamol manufacturers and suppliers

Here's how Pipelinepharma can help you connect with Paracetamol manufacturers and suppliers. Pipelinepharma is a B2B pharmaceutical marketplace that connects buyers and sellers of pharmaceutical products, including Paracetamol. The Pipelinepharma platform allows you to search for Paracetamol by name, strength, dosage form or country of origin. Pipelinepharma enables you to contact suppliers through the platform directly after you submit a product inquiry and our team qualifies it. You can request quotes, ask questions about products, and initiate deals with suppliers. 

More than 3000 Paracetamol products in different forms and strengths are available in the Pipelinepharma marketplace, listed under the Generics category. Many products have EU GMP approvals and several ready-to-file EU CTD dossiers.