Phentermine Hydrochloride is a pharmaceutical product used as an active ingredient in medications targeted to treat obesity. It is commonly known under its popular brand name of Ionamin and is most effective when it is used in combination with exercise and diet management. Phentermine Hydrochloride manufacturers and Phentermine Hydrochloride suppliers originally got it approved for medical use in the United States by the FDA in 1959. In subsequent years, it has emerged into the generic drugs space. Becoming extremely cost-effective and affordable for manufacturers to produce for sale. Currently, it can be found available for order on the pharmaceutical products list of distributors across the global medicine marketplace, where it is ready to purchase at a variety of cost and price points. Leading it to be the 210th most commonly prescribed medication in the United States, in 2017, with more than two million prescriptions. However, it was withdrawn from the medical marketplace in the United Kingdom in 2000. The combination medication fen-phen, which contained the active ingredient of Phentermine Hydrochloride, was withdrawn from the market in 1997 due to side effects.

Phentermine is a centrally acting drug that works by releasing adrenergic receptors from the lateral hypothalamus's postsynaptic vesicles. The activation of beta2-adrenergic receptors is caused by an increase in adrenergic receptors level in the synaptic cleft.

Phentermine belongs to a group of drugs termed sympathomimetic amine anorectic agents and it was introduced in 1959 as part of an anti-obesity combination drug. This medication functions through being an indirect-acting sympathomimetic agent that causes noradrenaline to be released from the presynaptic vesicles in the lateral hypothalamus. This increases noradrenaline concentration in the synaptic cleft, resulting in stimulation of beta2-adrenergic receptors. This culminates in an increase of the levels of norepinephrine and dopamine, and inhibition of neuropeptide Y which is a predominant signaling pathway for the induction of hunger. This combined effect produces a continuous flight-or-fight response in the body which reduces the hunger signal.

The final form of Phentermine Hydrochloride is dependent on the manufacturers and suppliers, as well as the specific distributors and orders. However, it can typically be found for wholesale and sale in the form of tablets and capsules. The usual adult dose for obesity is 8 mg orally 3 times a day 30 minutes before meals, or 15 to 37.5 mg orally once a day before breakfast or 1 to 2 hours after breakfast. According to the manufacturers’ literature, precaution should be taken in patients under the age of 17 and those with preexisting renal impairment.

Currently, at the time of writing, we have found 2 verified phentermine hydrochloride manufacturers and phentermine hydrochloride suppliers from online our global list of B2B sellers. These manufacturers, suppliers, and distributors are located in various countries such as Switzerland and Argentina. Each company listed on our online pharmaceutical database has been verified by the Pipelinepharma team. This process ensures seller reputability and limits both sourcing and negotiation dead ends for the potential buyer.

A cursory search reveals an approximate wholesale cost of a month's supply of phentermine hydrochloride in the United States is about US$2.55. As with all drugs, the specific cost will be highly dependent on the individual buyer. Therefore the prices indicated above solely serve as generalizations of the current market pricing and are not a definitive guide. Although prices on the online Pipelinepharma marketplace are confidential, manufacturers may choose to list the desired cost for their product to facilitate a quicker transaction. If so, this will be indicated alongside an ‘Accept’ and ‘Negotiate’ buttons, with a ‘Get offer’ button being displayed in the absence of a listed price.

Being a global B2B pharmaceutical online marketplace, Pipelinepharma is structured to simplify pharmaceutical deals by providing you with an intuitive interface that is easy to engage with. The selection of Phentermine Hydrochloride offerings can be narrowed down with the use of filters and easily weighed against one another according to medication prices and commercial terms. The advanced filters help you filter out the countries for these substance manufacturers and these substance suppliers that you are looking for. These also enable you to check the dossier status ofthis medicine and the GMP approvals of the different variants of Phentermine Hydrochloride. Also, each manufacturer or supplier product description contains essential information about this substance including clinical data, stability zones, countries where Phentermine Hydrochloride is already registered in. Manufacturers also have special, and delivery terms.

If you are a pharmaceutical licensing company or a distributor you can enter into deals or negotiations over these medicine offers with manufacturing companies after completing the free registration process and joining our online marketplace. This helps to ensure that you conclude the pharmaceutical deal at a reasonable cost and achieve the best cost/benefit ratio for your company while bypassing lengthy sourcing, negotiation, and ordering process. Once you have finalized a deal, you can look forward to a long-lasting business relationship with the manufacturers or suppliers. This way, the marketplace allows you as a distributor to skip the process of shortlisting product manufacturers every time you are looking for in-licensing or distribution deals.

To keep up to the quality standards other than Good Manufacturing Practice approvals that this medicine manufacturers list has, we qualify their companies before they are onboarded on the platform. This allows us to screen Phentermine Hydrochloride for the quality of the pharmaceutical products’ dossiers and protect against the risk of possible malpractices.