What does it do?
Praziquantel is prescribed as an anti-worm medicine for the treatment of a variety of
gastrointestinal and external parasites. It prevents newly hatched larvae (worm) of insects
from growing or multiplying in human bodies. Praziquantel is prescribed in the treatment of a
wide range of bacterial infections caused by worms. These worms enter human bodies
through the skin when the human body comes into contact with contaminated water. It is
used in preventing water-borne diseases in conjunction with more comprehensive water
treatment solutions like potable water, adequate sanitation, and removal of snails. As these
infections tend to be chronic, the use and availability of this medicine is global and is seen as
lifesaving medicine when given in time. Some of the common worms it helps cure are,
tapeworm, brain infection caused due to eating pork, infections from our pets, liver
infections, lung infections, and intestinal flukes.
Praziquantel is sold as Biltricide among other brand names.
Praziquantel was first made in the 1970s as a collaboration between Bayer A.G. and E.
Merck. It is an expensive drug and many companies have contributed to making the drug
more affordable in developing and underdeveloped countries. Praziquantel has been in
use in the United States since 1982. It also features on the World Health Organization's List
of Essential Medicines, a testimony to its efficacy. Nearly 230 million people worldwide were
treated using Praziquantel in 2018. This medicine if taken repeatedly over a number of
years can reduce and prevent death.
Dosage
Praziquantel is sold as a tablet. A normal dosage starts at 600 mg for adults. The prescribed
dosage varies by the type of worm it is being used to treat. The dosage can vary from 20mg
per day at intervals of 4-6 hours to 100mg in case of removing some of the other types of
worms.
How does it work?
Praziquantel works by killing the parasites. It can also paralyze these parasites, making
them die and fall off the blood vessel walls so the body can remove them naturally. It
achieves this by causing severe spasms and paralysis of the worms' muscles, which makes
them release contact with cell membranes, preventing the growth and also removing the
dead infection our body naturally. It works eventually by either completely destroying the
worm in the intestine and gets passed in the stool.
The wholesale cost of Praziquantel
Praziquantel (at 40 mg/kg body weight) cost of a single 600-mg tablet is about US$ 0.13 and
an average treatment is estimated to cost between US$ 0.20–0.30. but depending on the
country the price does vary a lot depending on the manufacturer.
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Some of the labelers in the USA
Bayer, Department of healthcare, Schering corporation, Avera McKennan hospital, and Par
Pharmaceutical, Inc.
Some of the packagers: Bayer Healthcare; Gallipot; KVP Pharma Plus Veterinaer Produkte GmbH; Schering Corp.
Praziquantel manufacturers | traders | suppliers
China: Ningbo distant chemicals, Hebei Veyong Animal Pharmaceutical Co, Zhejiang Hisun
Pharma, Shaoxing Hantai Pharma, Shanghai Desano Chem, Jiangsu Chengxin,
Shanghai Jiayi Pharma, Nanjing Pharma Factory, Zhejiang Genebest
Pharmaceutical Co Ltd, Shandong Zhanhua Yonghao.
France, Germany, Spain: PCAS and Merck; Chemo Iberica.
India: Cipla, Sequent Scientific, Solara Active Pharma; Aquatic Remedies Pvt Ltd.