Pyridostigmine

Pyridostigmine is a medication that improves strength in muscles in patients with a specific muscle disease called Myasthenia gravis. Myasthenia gravis is an autoimmune disorder in which the patients develop varying degrees of weakness in muscles. MS commonly affects the muscles in the Eyes, face, and causes difficulty in swallowing. It is also used with atropine to end the effects of medication that causes paralysis of the affected skeletal muscles. Cholinesterase in our body has inhibiting chemicals that prevent the breakdown of acetylcholine, causing a "jam" in the nervous system. Pyridostigmine bromide is sold as Mestinon (Valeant Pharmaceuticals), Regonol and Gravitor (SUN Pharma) amongst other brands. Hoffman-La Roche Laboratories in Switzerland first synthesized Pyridostigmine in 1945. It came into medical use in 1955. Pyridostigmine has earned in name of the list of medications recommended by the World Health Organization's List of Essential Medicines.

Forms and Dosage

Pyridostigmine is sold as a generic medication. Pyridostigmine is sold as an injectable solution, controlled-release tablets, tablet, and syrup forms. In the treatment of Myasthenia gravis, the patient is administered 600mg per day for maximum relief from the symptoms of MS. In reversing the effects of Non-depolarizing muscle relaxants, the patients are administered 20mg of the initial dose.

The wholesale cost of Pyridostigmine

The wholesale cost of Pyridostigmine in the USA is around $25-50 per month, whereas it costs significantly lesser in the developing world, where monthly supply costs at about US$7.17–65.93.

How does Pyridostigmine work?

Pyridostigmine prevents the breakdown of a natural substance called acetylcholine. Acetylcholine is responsible for the normal functioning of the muscles. Pyridostigmine slows down the breakdown of acetylcholine as competes with Acetylcholine for attachment to Acetylcholinesterase thus inhibiting Acetylcholinesterase, therefore increasing the efficiency of Cholinergic-transmission in the neuromuscular junction. Finding Pyridostigmine Manufacturers and Pyridostigmine Suppliers One of the fastest and easiest ways to find Pyridostigmine manufacturers and Pyridostigmine suppliers are to make use of Pipelinepharma's global B2B online marketplace for medicines and other pharmaceuticals. Usually, finding trusted manufacturers and supplies of specific drugs like Pyridostigmine can be a time-consuming challenge, but with Pipelinepharma's simple search engine and network of proven partners, the whole process becomes a lot easier. All you need to do to get started is to make use of our integrated search engine and start looking for suppliers or manufacturers of Pyridostigmine to work with.