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Country of origin : Albania

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telmisartan

Tablets 20 mg, 40 mg, 80 mg

Dossier type
EU CTD
Dossier status
Ready to file
Country of origin
Albania
GMP approvals
EU GMP
Comments
Ref: Micardis®
Manufacturer #252

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Telmisartan Manufacturers

Telmisartan belongs to the family of drugs named angiotensin II receptor blocker (ARB) with antihypertensive activity. It works by blocking a substance in the body that causes the blood vessels to tighten, as a result, telmisartan relaxes the blood vessels which in turn lowers the blood pressure and increases the supply of blood and oxygen to the heart. Lowering of blood pressure can reduce the risk of strokes and heart attacks. This drug is also used to lower the risk of heart attacks or stroke in patients above 55 years of age who have diabetes or heart problems. Telmisartan is used alone or in combination with other medications to treat high blood pressure.
Telmisartan is also used off-label for the management of Type 2 Diabetes associated nephropathy, heart failure and post-myocardial infarctions, particularly in patients who are unable to tolerate ACE inhibitors. This medication is advised as a prescription product, generic prescription product as well as mixture product. Before using this medication, the risk of taking the drug must be weighed against the benefits it provides. It is always recommended to consult a physician before taking telmisartan as this medication may interact with other drugs and health problems. Manufacturers of Telmisartan market this drug under the Brand name of Micardis, Kinzalmono. This drug is available only with the doctor’s prescription and it is available in the dosage form of Tablet which is administered orally. Telmisartan is available in varied dosage strengths of 20 mg, 40 mg, and 80 mg in white or off-white uncoated tablets. The recommended starting dose of Telmisartan in Hypertension is 40 mg once daily where most of the antihypertensive effect is present within 2 weeks and maximal reduction is attained after 4 weeks. The usual adult dose for Cardiovascular Risk Reduction is Telmisartan 80 mg tablet once a day.
Telmisartan can be taken with or without food and one should keep using this drug as directed by the physician and even when you feel well. Often High Blood Pressure has no symptoms and one may need to use this drug for the rest of the life. Telmisartan tablets should be stored at a temperature of 25 C (77 F) with excursions permitted between 15 and 30 C (59 and 86 F).

Wholesale Price of Telmisartan

In the US, the cost for telmisartan oral tablets 20 mg, 40 mg and 80 mg is around $ 8 for a supply of 30 tablets with per unit cost available for as low as $ 0.25 depending upon the pharmacy one visits.

Telmisartan - Mechanism of Action

Telmisartan belongs to Angiotensin II receptor blocker (ARB) family of drugs. Telmisartan selectively binds to angiotensin receptor 1 (AT1) and prevents the protein angiotensin II from binding. This prevents angiotensin II-induced vasoconstriction, stimulation and synthesis of aldosterone and anti-diuretic hormone (ADH), thereby decreasing the aldosterone production and preventing aldosterone stimulated sodium retention and potassium excretion. Overall, telmisartan’s physiologic effects lead to reduced blood pressure, lowers aldosterone levels, reduced cardiac activity and increased excretion of sodium.

Finding Telmisartan Manufacturers and Suppliers

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