Zolpidem Manufacturer
Currently, we haven't found any verified zolpidem manufacturers or zolpidem suppliers from our global list of sellers. For more information about sourcing wholesale supplies of zolpidem, please speak to one of Pipelinepharma's customer support representatives on +370-5-207-5842 or send an email to [email protected]. We will get back to you as soon as possible Zolpidem is sold under the trade name Ambien among many others and is classified as nonbenzodiazepine or sedative-hypnotic. This pharmaceutical medication is commonly administered through oral and sublingual routes in the form of a tablet, through the oro-mucosal route in the form of a spray, and through the rectal route with the onset of action less than or equal to 30 minutes. It is 70% bioavailable when administered by mouth and has a protein binding of 92%. It is extensively metabolized by the liver through CYP3A4 and CYP1A2, resulting in the metabolites zolpidem 6-carboxylic acid and zolpidem phenyl-4-carboxylic acid which are excreted approximately 56% through the kidney and 34% through feces. The elimination half-life of this drug is in between 2.5-3 hours and the duration of action is 3 hours. It is available in the immediate-release dosage form in the doe strength of 5mg for women and 10mg for men, extended-release dosage form in dosage strengths of 6.25mg for women, and 12.5mg or 6.25mg for men. It has a moderate type of dependence liability that's why its legal status is ''Prescription Only Medication''. It is indicated primarily in the short-term treatment of sleeping problems and can only be used after cognitive behavioral therapy for insomnia and behavioral changes. Associated side effects include sleepiness, headache, nausea, diarrhea, memory problems, and hallucinations. FDA has not yet assigned any pregnancy category to this drug, but it can be used during pregnancy with extreme caution. It is evidenced to release in very little amount in the human breastmilk and due to its short half-life is expected to not affect infants, but it is necessary to monitor the infant for adverse effects like hypotonia, sedation, and respiratory sedation. This pharmaceutical medication is known to have drug interactions with Sodium Oxybate, Ketoconazole, and Rifampin. It is contraindicated in patients with conditions like confusion, suicidal thoughts, alcohol intoxication, depression, aggressive behavior, attention deficit syndrome with hyperactivity, and myasthenia gravis. In case of overdose, Flumazenil is recommended which can be used to reverse its effects. This drug was first approved by FDA on December 16, 1992, for the generic name Zolpidem tartrate under the trade name Ambien, manufactured by Lorex Pharmaceuticals for medical use later it became available in generic medication in 2007. It is included in Schedule IV controlled substances under the Controlled Substances Act of 1970. According to a survey carried out in 2019 in the United States, it was 47th most common drug prescribed with more than 15 million prescriptions.
How does Zolpidem work?
Being a GABA receptor agonist it increases GABA effects in the central nervous system by binding to GABA receptor covalently.
The wholesale price of Zolpidem
An online search for the wholesale price of 30 tablets of Zolpidem tartrate 10mg reveals its cost to be approximately 69.99 dollars. It will vary from store to store.
Sourcing the Zolpidem Manufacturers and Suppliers
Pipelinepharma is a B2B global pharmaceutical licensing marketplace that lets buyers and distributors find suppliers and manufacturers of zolpidem and other pharmaceutical products. Instead of travelling to conferences and meetings to find new companies to do business with, you can discover them within a few clicks of a mouse. Use the integrated search engine to look for distributors of zolpidem or other drugs that are for sale all across the globe. You can further refine your search by using such filters as forms, dossier type, category and therapy area. This online platform is much more than a contacts list of manufacturers and suppliers around the world. It is also an introduction to a wealth of potential business opportunities.
Establishing commercial ties
Each medication listed on the site includes a product description with a lot of information such as manufacturing site approvals, regulatory status, form, dose, dossier status and dossier type. Other details include a dossier license fee for the chosen market and standard pack sizes. If there is an offer, you have two options. Either order it or reach out to the supplier to negotiate terms using the one-page term sheet and integrated messaging system. If there is no offer, you can request a quotation for the wholesale cost or other criteria from the seller of zolpidem. The entire process is geared to save buyers and sellers time and to make it easy to negotiate and agree with requests for the wholesale selling and purchasing of pharmaceutical products. Sellers are attracted to the online marketplace for a number of reasons. They can list an unlimited amount of products for free, including zolpidem, and these will be seen by a variety of qualified buyers.
Quality Assurance
In the pharma industry, the quality of the medication is of the utmost importance. In addition to providing evidence of good manufacturing practices that makers of zolpidem have to comply with, Pipelinepharma verifies each company before they are able to list their products. Manufacturers have to answer a standard industry-specific pre-auditing questionnaire where they provide all the details about the dossier and the product.
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